Pittsburgh Steelers
| Week | Opponent | Date (EST) | TV |
|---|---|---|---|
| 1 | @  Cincinnati | Sun Sep 11 1:00 PM | CBS |
| 2 | vs.  New England | Sun Sep 18 1:00 PM | CBS |
| 3 | @  Cleveland | Thu Sep 22 8:15 PM | Amazon Prime Video |
| 4 | vs.  NY Jets | Sun Oct 2 1:00 PM | CBS |
| 5 | @  Buffalo | Sun Oct 9 1:00 PM | CBS |
| 6 | vs.  Tampa Bay | Sun Oct 16 1:00 PM | FOX |
| 7 | @  Miami | Sun Oct 23 8:20 PM | NBC |
| 8 | @  Philadelphia | Sun Oct 30 1:00 PM | CBS |
| 9 | BYE | -- | -- |
| 10 | vs.  New Orleans | Sun Nov 13 1:00 PM | FOX |
| 11 | vs. Cincinnati | Sun Nov 20 8:20 PM | NBC |
| 12 | @  Indianapolis | Mon Nov 28 8:15 PM | ESPN |
| 13 | @  Atlanta | Sun Dec 4 1:00 PM | CBS |
| 14 | vs.  Baltimore | Sun Dec 11 1:00 PM | CBS |
| 15 | @  Carolina | Sun Dec 18 1:00 PM | CBS |
| 16 | vs.  Las Vegas | Sat Dec 24 8:15 PM | NFL Network |
| 17 | @ Baltimore | Sun Jan 1 1:00 PM | CBS |
| 18 | vs. Cleveland | Sun Jan 8 1:00 PM | CBS |