| AWAY | HOME | DATE (EST) | TV | LOCATION |
|---|---|---|---|---|
 Indianapolis | @  Denver | Thu Oct 6 8:15 PM | Amazon Prime Video | Empower Field at Mile High, Denver, CO |
 NY Giants | @  Green Bay | Sun Oct 9 9:30 AM | NFL Network | Tottenham Hotspur Stadium, London |
 Pittsburgh | @  Buffalo | Sun Oct 9 1:00 PM | CBS | Highmark Stadium, Orchard Park, NY |
 LA Chargers | @  Cleveland | Sun Oct 9 1:00 PM | CBS | FirstEnergy Stadium, Cleveland, OH |
 Chicago | @  Minnesota | Sun Oct 9 1:00 PM | FOX | U.S. Bank Stadium, Minneapolis, MN |
 Detroit | @  New England | Sun Oct 9 1:00 PM | FOX | Gillette Stadium, Foxboro, MA |
 Seattle | @  New Orleans | Sun Oct 9 1:00 PM | FOX | Caesars Superdome, New Orleans, LA |
 Miami | @  NY Jets | Sun Oct 9 1:00 PM | CBS | MetLife Stadium, East Rutherford, NJ |
 Atlanta | @  Tampa Bay | Sun Oct 9 1:00 PM | FOX | Raymond James Stadium, Tampa, FL |
 Tennessee | @  Washington | Sun Oct 9 1:00 PM | CBS | FedExField, Landover, MD |
 Houston | @  Jacksonville | Sun Oct 9 1:00 PM | CBS | TIAA Bank Field, Jacksonville, FL |
 San Francisco | @  Carolina | Sun Oct 9 4:05 PM | CBS | Bank of America Stadium, Charlotte, NC |
 Dallas | @  LA Rams | Sun Oct 9 4:25 PM | FOX | SoFi Stadium, Inglewood, CA |
 Philadelphia | @  Arizona | Sun Oct 9 4:25 PM | FOX | State Farm Stadium, Glendale, AZ |
 Cincinnati | @  Baltimore | Sun Oct 9 8:20 PM | NBC | M&T Bank Stadium, Baltimore, MD |
 Las Vegas | @  Kansas City | Mon Oct 10 8:15 PM | ESPN | GEHA Field at Arrowhead Stadium, Kansas City, MO |