New England Patriots
| Week | Opponent | Date (EST) | TV |
|---|---|---|---|
| 1 | @  Miami | Sun Sep 11 1:00 PM | CBS |
| 2 | @  Pittsburgh | Sun Sep 18 1:00 PM | CBS |
| 3 | vs.  Baltimore | Sun Sep 25 1:00 PM | FOX |
| 4 | @  Green Bay | Sun Oct 2 4:25 PM | CBS |
| 5 | vs.  Detroit | Sun Oct 9 1:00 PM | FOX |
| 6 | @  Cleveland | Sun Oct 16 1:00 PM | CBS |
| 7 | vs.  Chicago | Mon Oct 24 8:15 PM | ESPN |
| 8 | @  NY Jets | Sun Oct 30 1:00 PM | CBS |
| 9 | vs.  Indianapolis | Sun Nov 6 1:00 PM | CBS |
| 10 | BYE | -- | -- |
| 11 | vs. NY Jets | Sun Nov 20 1:00 PM | CBS |
| 12 | @  Minnesota | Thu Nov 24 8:20 PM | NBC |
| 13 | vs.  Buffalo | Thu Dec 1 8:15 PM | Amazon Prime Video |
| 14 | @  Arizona | Mon Dec 12 8:15 PM | ESPN |
| 15 | @  Las Vegas | Sun Dec 18 8:20 PM | NBC |
| 16 | vs.  Cincinnati | Sat Dec 24 1:00 PM | CBS |
| 17 | vs. Miami | Sun Jan 1 1:00 PM | CBS |
| 18 | @ Buffalo | Sun Jan 8 1:00 PM | CBS |